deCODE Cancer

deCODE Basal Cell Carcinoma test

Includes 6 markers that together define the 9% of the population that has 1.5 to 5.1 fold the general population risk (50 – 400% increase) of developing basal cell carcinoma.

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The deCODE Cancer Scan detects the same risk factors and markers included in our individual tests for:

Breast Cancer (deCODE BreastCancer™) and
Prostate Cancer (deCODE ProstateCancer™)

together with:

Basal Cell Carcinoma, Bladder Cancer, Colorectal Cancer, Lung Cancer, Ovarian Cancer, Testicular Cancer and Thyroid Cancer.

Basal Cell Carcinoma

Screening and prevention

How the deCODE Basal Cell Carcinoma test can help.

A simple self examination of the skin and knowing what to look for, and before that being aware of ones risk, especially if there has been a prolonged sun expose and a positive family history are crucial for early detection.

The 6 deCODE Cancer markers for basal cell carcinoma which deCODE’s scientists have shown to associate with increased risk of developing this type of skin cancer (TGCT) are located on chromosomes 1p36, 1q42 ,5p15.33, 7,9p21 and 12 respectively.

The two markers on chromosome 1 and the marker on chromosome 7 have few possible susceptibility candidate genes by function and location. The markers on chromosomes 5, 9 and 12 are located near the more suspicious TERT, CDKN2A/B and KRT5 gene respectively.

At present, the necessary scientific information to interpret the genetic risk for individuals of other ethnicities than of European descent is not available.

This content was last reviewed on January 25, 2011.